Skin rashes, which are the only sign of Kirle's disease, can be located on various parts of the body, so it is not necessary to talk about the typical localization of the pathological process. Distinctive features of changes in this pathology are: the appearance of the first signs in the armpits. This phenomenon is observed often, but not in all 100% of cases; often changes are localized on the extensor surfaces of the elbow and knee joints, the outer surface of the lower leg and forearm; in some cases, the disease is disseminated, changes are localized on the limbs, scalp, face and other parts of the body; rashes in Kirle's disease are never observed on the palmar surface of the hand and the plantar surface of the foot.
It cannot be said that Kirle's disease has any peculiarities when localized on the face, however, changes are quite often found on the scalp and face, they are a great aesthetic disadvantage and cause psychological suffering. Since rashes are the only manifestation of the disease, and there are no subjective sensations, patients often seek help precisely when changes are localized on the face or other open areas of the body. The psychological problems caused by Kirle's disease are most pronounced precisely in the presence of changes on the face; in all other senses, this localization of the disease does not differ in any way from all other forms of this pathology.